[Solved] Assignment 4 605.451 Principles of Computational Biology

1. Begin Using CLUSTAL method to align the following amino acid sequences with the popular score matrix (Blossum62, Gap open penalty = -11, Gap extension penalty= -1) (100 points).

S1: ALSKC

S2: TNSDM

S3: NASKK

S4: NTSDA

What to turn in

• Turn in your similarity matrix (34 points).
• Turn in the guide tree (33 points).
• Turn in the multiple alignments (33 points)